Synthesis and Antioxidant Properties of Some [2-Methoxy-5-(3-alkyl-4,5-
dihydro-1H-1,2,4-triazol-5-one-4-yl)-azomethinphenyl benzoates

Ã…Âžule BahÃƒÂ§eci; Nuri YÃ„Â±ldÃ„Â±rÃ„Â±m; ÃƒÂ–zlem GÃƒÂ¼rsoy-Kol; Murat Beytur; Haydar YÃƒÂ¼ksek

Abstract

Synthesis and Antioxidant Properties of Some [2-Methoxy-5-(3-alkyl-4,5- dihydro-1H-1,2,4-triazol-5-one-4-yl)-azomethinphenyl benzoates

Author(s): Ãâ¦ÃÅ¾ule BahÃÆÃÂ§eci, Nuri YÃâÃÂ±ldÃâÃÂ±rÃâÃÂ±m, ÃÆÃâzlem GÃÆÃÂ¼rsoy-Kol, Murat Beytur and Haydar YÃÆÃÂ¼ksek

In this paper, ten novel [2-Methoxy-5-(3-alkyl-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl)-azomethinphenyl benzoates (4) were obtained with the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) and 3- benzoxy-4-methoxbenzaldehyde (3), which has been synthesized by the reaction of 3-hydroxy-4- methoxybenzaldehyde with benzoyl chloride by using triethylamine. The novel synthesized compounds were identified by IR, 1H NMR, 13C NMR and UV spectral data. Besides, the newly synthesized compounds were analysed for their in vitro potential antioxidant capacities in three different techniques. Compounds 4e, 4g and 4i demonstrated significant activity for metal chelating effect.

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