Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Synthesis and antiprotozoal activity of nitro and halogeno substituted some novel mercaptobenzimidazole derivatives

Author(s): Pratik P.Maske, Sachin G Lokapure, Dhanashri Nimbalkar, John I.Disouza

The earliest report of Benzimidazole derivatives antibacterial activity appeared in 1964, and more recently we have found two groups of substituted benzimidazoles, namely the 5,6-dinitro and 2-trifluoromethyl derivatives, to be promising candidates for antimicrobial drugs. In this paper we present new data on the antimicrobial and antiprotozoal activities of 5,6-dinitro and 2-dialkylaminosubstituted benzimidazoles.


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