Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Synthesis and Biological Activity Studies of Novel Arylazo Pyrazole Derivatives

Author(s): Revanasiddappa BC, Jose N

A series of novel 3,5-dimethyl arylazo pyrazoles (3a-i) were synthesized by reacting various oxybutyrates with methyl paraben (1) in glacial acetic acid medium. The key intermediate oxybutyrates (2a-i) were prepared from substituted phenyl diazonium salts and acetyl acetone in alcohol medium. The structures of the synthesized compounds have been established on the basis of spectral data (IR, 1H-NMR, Mass). The antibacterial and antifungal activity of the compounds has also been evaluated. Few of them have shown significant antifungal activity when compared to standard Flucanazole.

Full-Text PDF

SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan