GET THE APP

Synthesis and biological evaluation of ?²-carboline derivatives as an anxiolytic agents | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis and biological evaluation of ?²-carboline derivatives as an anxiolytic agents

Author(s): Keerti Vishwakarma, Shilpi Jain, Harish Rajak, RS Pawar and PK Singour*

In our present research work, we have synthesized a series of β-carboline derivatives and evaluated for their anxiolytic activity. The structures of the compounds have been confirmed by IR and NMR spectroscopy. Newly synthesized compounds were tested for anxiolytic activity using elevated plus maze model. Among the synthesized compounds, N-(4-hydroxyphenyl)-9H-β-carboline-3-carboxamide (4a) was found to be most active with the maximum no. of entries in open arm and time spent in open arm.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Recommended Conferences
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry