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Synthesis and Biological evaluation of novel (4-chlorophenyl) ((1R, 3r, 5S)-3- (phenyl amino)-8-aza-bicyclo [3.2.1] octan-8-yl) methanone derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Synthesis and Biological evaluation of novel (4-chlorophenyl) ((1R, 3r, 5S)-3- (phenyl amino)-8-aza-bicyclo [3.2.1] octan-8-yl) methanone derivatives

Author(s): Krishna Palaa, S. M. Reddy, Bijivemula N. Reddyb, Madhvesh Pathak and C. Nageshwara Reddy

In the present study, we have carried out the synthesis of novel (4-chlorophenyl) ((1R, 3r, 5S)-3-(phenyl amino)-8- aza-bicyclo [3.2.1] octan-8-yl) methanone derivatives. The structure of the newly synthesized compounds was elucidated by IR, 1HNMR, 13CNMR, 19FNMR, Mass spectral data and CHN elemental analysis. Further all the novel derivatives were investigated for their invitro antibacterial activity.


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