Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Synthesis and Biological Evaluation of Potent Benzimidazolone Derivatives

Author(s): Jabali J Vora, Dinesh R Patel, Nilesh V Bhimani and Parag V Ajudia

Some benzimidazolone derivatives containing piperidine ring derivatives were synthesized and characterization was done by CHN analysis, IR, Mass and 1H NMR spectral data. The benzimidazolone derivatives were evaluated for their antibacterial activity against both grampositive and gram-negative bacteria. The bacterial strengths were E. coli, B. subtilis, B. megaterium, P. fluorescens and found good results.


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