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Synthesis and biological evaluation of some new 3-c yano-2-amino substituted chromene derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Synthesis and biological evaluation of some new 3-c yano-2-amino substituted chromene derivatives

Author(s): Rangisetty Mallikarjuna 1 , Yedukondalu M. 2 , P. S. S. D. Varma 2 , Vandana 3 * and D. M. Manidhar 4

Chromenes are the one of the important class of het erocyclic compounds which poses wide range of pharm aceutical and biological importance. Different functional gro ups at different positions in the core structure of chromene deliberately yields novel derivatives which play a prominent role in in the field of medicinal chemi stry. In this work one pot synthesis of a few new series of 2-amino- 3-cyano-4H-chromene derivatives were designed, syn thesized , characterized and biological activity like anti-bac terial and anti-fungal studies were screened, where most of the compounds have shown good growth inhibition acti vity.


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