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Synthesis and characterization of a new peptide analogue: 2-Amino-N-(2-amino-ethyl)-3-phenyl-propionamide | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Synthesis and characterization of a new peptide analogue: 2-Amino-N-(2-amino-ethyl)-3-phenyl-propionamide

Author(s): Dipanjan Majumdar1, Chandra Nath Saha2, Sanjib Bhattacharya3*

In the present study, a new dipeptide analogue namely 2-amino-amino ethyl)-3-phenylpropionamide was synthesized by liquid phase synthesis from L-phenylalanine and ethylenediamine. The intermediates and the final compound were analyzed by analytical thin layer chromatography and characterized by 1H NMR, D2O exchange NMR and mass spectral analyses to ascertain the purity and elucidate the chemical structure. This is the first experimental report of the synthesis and characterization of this compound.


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