Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Synthesis and characterization of new 1,2-diazepine derivative

Author(s): Majal Sapnakumari, Badiadka Narayana, Seranthimata Samshuddin and Balladka Kunhanna Sarojini

The reaction of (1Z)-1-[(2E)-3-(4-bromophenyl)-1-(4-fluorophenyl)prop-2-en-1-ylidene]-2-(2,4-dinitrophenyl) hydrazine (2) with ethyl chloroacetate in the presence of base affords a new 1,2-diazepine derivative, 5-(4- bromophenyl)-1-(2,4-dinitrophenyl)-3-(4-fluorophenyl)-1H-1,2-diazepin-6-ol (3). The intermediate 2 in turn prepared from 4-bromo-4'-fluorochalcone (1). The structure of the newly synthesized compound is characterized by IR, NMR and mass spectral data


PDF

FIND ARTICLES
SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan