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Synthesis and characterization of some novel isoxazoles via chalcone intermediates | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Synthesis and characterization of some novel isoxazoles via chalcone intermediates

Author(s): Kapubalu Suneel Kumar, Kovvuri Tatendra Reddy, Appikonda Vamsikanth, Gudaparthi Omprakash, P. K. Dubey

The synthesis and characterization of some novel isoxazoles derivatives have been presented. Acylation of resorcinol followed by nuclear prenylation with isoprene gives Chroman. Chroman on treatment with p-substituted benzaldehydes affords substituted chalcones. Isoxazoles have been prepared from chalcones by treating with hydroxylamine hydrochloride. The structure of isoxazoles has been characterized by spectral analysis.


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