Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Synthesis and characterization of some organic molecules containing ligand

Author(s): Sefali S. Patel, Khushbu K. Mehta and Asha D. Patel

The new ligand 2-hydroxy-4-(methyl((5-(4-sulfamoyl phenyl carbamoyl) furan-2-yl)ethyl amino)benzoic acid (HMSPCFEAB) prepared by condensation reaction between 4-(((5-(ethoxy carbonyl)furan-2-yl)methyl)ethyl amino)salicylic acid and Sulphanilamide was give. It was characterized by elemental analysis and spectral studies. The transition metal chelates Cu+2,Ni+2,Co+2,Mn+2and Zn+2 of HMSPCFEAB were prepared and characterized by metal to ligand ratio, IR spectra and reflectance spectroscopies and magnetic properties. The antifungal activity of HMSPCFEAB and its metal chelates was examined against various fungi.


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