A facile route for the synthesis of tetrasubstituted imidazole has been developed; the one pot synthetic protocol allows the efficient synthesis of biologically important scaffolds. By using alkyne as the key starting material, which was oxidized in situ to get active carbonyl species? The key reaction involved in this synthesis is formic acid catalyzed oxidation, I2 mediated oxidation and Silica supported cyclization to give tetrasubstituted imidazole.
Select your language of interest to view the total content in your interested language
Der Pharma Chemica received 11575 citations as per Google Scholar report