GET THE APP

Synthesis and evaluation of new phenylamino-thiadiazolo-oxadiazolo-1, 3-benzoxazoles for their antifungal and anti-inflammatory activity | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis and evaluation of new phenylamino-thiadiazolo-oxadiazolo-1, 3-benzoxazoles for their antifungal and anti-inflammatory activity

Author(s): L. Srikanth, Usha Naik, Ramesh Jadhav, N.Raghunandan, J. Venkateshwar Rao and K. Raj manohar

In view of various biological activities of benzoxazoles, thiadiazoles and oxadiazole derivatives, it was our interest to prepare benzoxazole derivatives involving 1,3,4-thiadiazole and 1,3,4- oxadiazole nucleus and evaluate them for antifungal and anti-inflammatory activity using carrageenan induced rat paw edema model. The structures of all the synthesized compounds were characterized by IR, 1H-NMR and MASS spectral data. All the synthesized compounds were screened for antifungal and anti-inflammatory activity. Among all the active compounds thiadiazole and oxadiazole derivatives showed good activity.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry