GET THE APP

Synthesis and in vitro antibacterial evaluation of 2,4-dintrophenol incorporated azo dyes molecules | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis and in vitro antibacterial evaluation of 2,4-dintrophenol incorporated azo dyes molecules

Author(s): Ramesh F. Pagariya and Nandkishor S. Thakre

Synthesis of most azo dyes involves diazotization of a primary aromatic amine, followed by coupling with one or more nucleophiles. Thus, benzoic, phenolic, salicylic and naphtholic compounds acts as nucleophiles and undergoes coupling reactions. In this study, a series of azo compounds were synthesized via the diazotization of different aromatic amines followed by coupling with 2, 4, dinitrophenol. These compounds were characterized by elemental analysis, IR, 1HNMR and MASS spectroscopic techniques. The synthesized compounds have been tested in vitro against human pathogens in order to assess their antibacterial properties using disk diffusion method. The compounds analysed for its antibacterial action showed moderate to significant inhibitory effect at some specific concentrations against the tested pathogens.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 15261

Der Pharma Chemica received 15261 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry