Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ilbet

süperbetin giriş

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

agariookey oyna istanbul okey

Abstract

Synthesis and Microbial Screening of (2-Propyl-Benzimidiazole-1-yl) Acetic Acidbenzylidene Hydrazide

Author(s): Maqdoom Farooqi, Syed Nazimuddin

In the present work, a simple convenient and high yielding synthetic route has been employed for the synthesis of targeted molecules (2-propylbenzoimidazol- 1-yl)-acetic acid benzylidene-hydrazid (1a-d) and 4-(Benzylidene-amino)-5-(2-propyl-benzoimidazol-1-ylmethyl)-4H- [1,2,4]triazole-3-thiol(2a-d). The structures were confirmed by Fourier Transform Infrared Spectroscopy (FT-IR), Proton Nuclear Magnetic Resonance (H1NMR) and physical properties. The synthesized compounds were screened for anti-microbial analysis against Bacillus subtilis, Staphylococcus aureus, Candida albicans and Escherichia coli, Aspergillus niger. The compounds are found to be highly active, hence forth, could be attractive lead molecules for developing new therapeutics against tested microorganisms.


PDF

rokettube brazzers