Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Synthesis and pharmacological studies of some bivalent metal complexes with Schiff based ligand derived from xipamide

Author(s): Suparna Ghosh

The Zn(II) and Hg(II) complexes of Schiff base derived from Salicylaldehyde and Xipamide have been synthesized keeping in view that some metal complexes are found to be more potent than their parent drugs. The complexes of the type ML2 have been synthesized and characterized on the basis of elemental analysis, conductivity, magnetic measurements, IR and electronic spectral studies. The conductivity data of the complexes also suggests their nonelectrolytic nature. Comparative antimicrobial behavior and particle size analysis of Schiff base with their complexes has also been studied


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