Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Synthesis and study of 2-hudroxy substituted Chalcone dibromide effects on different crop plant growth

Author(s): Nilima A. Kalambe, Atish K. Maldhure and P. B. Raghuvanshi

The synthesized 3-bromo-5-chloro-2-hydroxyacetophenone on condensation with anisaldehyde and benzaldehyde) gives corresponding 2-hydroxy substituted chalcone. On bromination, 2-hydroxy substituted chalcone gives 5- chloro-2-hydroxy chalcone dibromide, 5-chloro-2-hydroxy -4-methoxy chalcone dibromide, 3-bromo-5-chloro-2- hydroxy chalcone dibromide and 3-bromo-5-chloro-2-hydroxy-4-methoxy chalcone dibromide respectively. The structure of ligands was elucidated on the basis of molecular weight, elemental analysis and spectral data.