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Synthesis, antibacterial and antifungal properties of novel organophosphorus compounds | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Synthesis, antibacterial and antifungal properties of novel organophosphorus compounds

Author(s): Kalpana Chaturvedi, Ashish Kumar, Abhinav Mishra

A series of biologically active organophosphorus compounds have been synthesized by the reactions of Phenylphosphonic dichloride / 4-Chlorophenyl dichlorophosphate with 5-( phenyl / substituted phenyl )-1,3,4- thiadiazol-2-ylcarbamodithioic acids . The compounds have been characterized on the basis of elemental analyses and spectral (IR, 1H NMR 31P NMR) data. All the compounds were screened for their anti microbial activity. They were found to possess significant anti-microbial activity.


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