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Synthesis, antimicrobial and pharmacological evaluation of substituted novel benzimidazoles | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Synthesis, antimicrobial and pharmacological evaluation of substituted novel benzimidazoles

Author(s): V. Mohan Goud*, N. Sreenivasulu, Avanapu Srinivasa Rao and Srinivas Chigiri

The present work is carried out for the synthesis of benzimidazole derivatives with well established procedures. A new series of benzimidazole derivatives were synthesized and the structures of these compounds were confirmed by IR, HNMR and Mass Spectroscopy. The title compounds were screened for analgesic and anti inflammatory activities by biological evaluation method and also for other possible pharmacological activities including antibacterial activity. Among the synthesized compounds, some have shown promisingly significant analgesic, anti- inflammatory activites and moderate antibacterial activity.


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