Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Synthesis, Antimicrobial Evaluation of some New Heterocycles Derived from N-Substituted Saccharin

Author(s): Redha Ibrahim AL-Bayati, Athraa Hameed Mekky

A series of novel five membered heterocycles (oxazole, thiazoles, imidazolidine, 2-thioxoimidazolidine) derived from N-substituted saccharin were synthesized and identified using IR, 1HNMR and 13CNMR spectra. The novel compounds were tested for their antimicrobial activities against several Gram-positive and Gram-negative bacterial species