Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


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Synthesis, characterisation and biological applications of conducting poly (p- amino phenol) and its nano compound

Author(s): Thenmozhi G, JayaKumar D, Mohanraj Gopalswamy and Jaya Santhi R

The oxidative chemical polymerizations of para aminophenol was synthesized in acidic medium using potassium dichromate as an oxidant at 00C and its nano compound was synthesized using an anionic surfactant Sodium Dodecyl Sulphate. They were characterized by FT- IR, UV-VIS, 1H-NMR, TGA, SEM and TEM. The formation of benzenoid and quinonoid structure was confirmed from the FT-IR, 1H-NMR and UV studies and the thermal studies confirms that the poly nano compound is more stable than the corresponding polymer. The conductance was measured and found to be semiconducting in nature. The resulting polymer and its nano compound were analyzed for its antioxidant activities using DPPH assay and the antibacterial activities by agar well cut diffusion method against two bacterial stains Staphylococcus aureus (gram +ve) and Escherichia coli (gram-ve). The antioxidant and antibacterial activities of poly (p–aminophenol) nano compound is greater than the corresponding polymer and they were concentration and the time dependant. The increased activities of poly nano compound may be due increase in surface area because of its smaller size and these properties can be considered in the field of biomaterials in biomedical areas.


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