Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

Synthesis, characterization and antimicrobial activities of 1-Acetyl-5-(substituted phenyl)-{3-[4-(2-methyl-4-benzylidene-5-oxo-imidazol-1-yl)]phenyl}-4,5-dihydropyrazol

Author(s): P. S. Patel, R. A. Shah, D. K. Trivedi, P. J. Vyas

1-acetyl-5-(substituted phenyl)-{3-[4-(2-methyl-4-benzylidene-5-oxo-imidazol-1-yl)]phenyl} -4,5-dihydropyrazol have been prepared by the refluxation for three hours of 5-(substituted phenyl)-{3- [4- (2-methyl- 4-benzylidene-5-oxo-imidazol-1-yl)]phenyl}-4,5-dihydropyrazol and acetic acid. the intermediate P-3 have been prepared by the refluxation for three hours of 4-benzylidene-1-{4-[3-(substituted phenyl)prop-2-enoyl] phenyl} -2 –methyl -imidazol-5-one with hydrazine hydrate in presence of ethanol the intermediate P-2 synthesized by the condensation of 1-(4-acetylphenyl)-4-benzylidene-2-methyl-imidazol-5-one with various aldehydes.


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