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Synthesis, characterization and antimicrobial activities of imidazo-[2,1,b][1,3,4]-thiadiazoles | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Synthesis, characterization and antimicrobial activities of imidazo-[2,1,b][1,3,4]-thiadiazoles

Author(s): Manjunatha K, Boja Poojary, Vasantha Kumar, Prajwal L. Lobo, Jennifer Fernandes and Chandrashekhar C.

A series of imidazo[2,1-b][1,3,4]-thiadiazoles (6a-p) were synthesized by a condensation reaction of 2-amino-5- substituted-[1,3,4]thidiazoles (5a-b) with various substituted phenacyl bromides. All structures of the newly synthesized compounds were elucidated by elemental analyses and spectral data. The new compounds were tested for their in vitro antimicrobial activities.


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