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Synthesis, characterization and antimicrobial activity of N'-(substituted phenyl)-2-(1H-azol-1-yl) acetamides | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Synthesis, characterization and antimicrobial activity of N'-(substituted phenyl)-2-(1H-azol-1-yl) acetamides

Author(s): Rambhau P. Gore

A facile two-step synthesis of N'-(substituted phenyl)-2-(1H-azol-1-yl) acetamides have been carried out by acylation of substituted aromatic primary amines and subsequent alkylation of N-chloroacetyl aryl amineswith some azoles in good yields. The synthesized compounds have been characterized by IR, 1H NMR, 13C NMR and Mass spectral data.


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