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Synthesis, Characterization and Antimicrobial Activity of Some 4, 5- Dihydro. 3, 5- Diaryl- N- [(Arylamido/Imido)- Alkyl] Pyrazole- 1 Carbothioamides/Carboxamides | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Synthesis, Characterization and Antimicrobial Activity of Some 4, 5- Dihydro. 3, 5- Diaryl- N- [(Arylamido/Imido)- Alkyl] Pyrazole- 1 Carbothioamides/Carboxamides

Author(s): Soniya Singh*, V.K. Pandey and P. K. Shukla

Synthesis of substituted pyrazoles derivatives was undertaken employing a convenient and easily accessible procedure. In this article some 4, 5- dihydro- 3, 5- diaryl- N- [(anylamidolimido) alkyl] pyrazole- 1- carbothrioamides/carboxamides were synthesized from 1, 3- diaryl- prop- 2- enes as starting material for their characterization and antimicrobial activity involving five fungal and four bacterial strain in vitro. Synthesized substituted pyrazole compounds were obtained in the yields varying 53-68%.


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