Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.
Abstract
Synthesis, characterization and antimicrobial evaluation of dicoumarinyl substituted pyrazolyl pyridines
Author(s): Kaushik N. Kundaliya, Yogita L. Chovatiya, Niraj H. Patel and D. I. BrahmbhattThe synthesis of various 2,6-di(coumarin-3-yl)-4-(1-phenyl-3–aryl-1H-pyrazol-4-yl)pyridines (5a-r) have been carried out by the reaction of 3-coumarinoyl methyl pyridinium bromide salts (4a-c) with various 3-[3-(1-phenyl-3- aryl-1H-pyrazol-4-yl) acryloyl] coumarins (coumarin chalcones) (3a-f) in the presence of ammonium acetate in refluxing acetic acid. The synthesized compounds were fully characterized by IR, 1H-NMR, 13C-APT and representative Mass spectral data. The synthesized compounds were screened for in vitro antimicrobial activity using Broth micro dilution method.
Select your language of interest to view the total content in your interested language
Google Scholar citation report
Citations : 25868
Der Pharma Chemica received 25868 citations as per Google Scholar report
Der Pharma Chemica peer review process verified at publons
DOWNLOADS
