Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Synthesis, Characterization and Antimicrobial study of piperidine-2,6-diones derivatives

Author(s): AP Rajput and Deepak V Nagarale

The piperidine ring is a structural feature of many alkaloids and drug [1] candidates and there were thousands of piperidine compounds mentioned in clinical and preclinical studies[2]. The piperidine ring system is one of the commonest structural sub units in natural compounds. Several substituted piperidines display important biological properties like antiviral activity. We have used a simple and highly efficient method for the synthesis of 1-(4- chlorophenyl) piperidine-2,6-diones. The reaction was optimized by using various solvents with some modifications in reaction conditions. The synthesized compounds are a precursor for dichlorodialdehydes 1, 4-DHP. Characterization of all synthesized piperidine-dione derivatives was done by analytical technique such as FTIR, 1HNMR. The resulting compounds possess symmetrical structures [3] and have high yields. All the compounds were screened for antimicrobial activities.


PDF

FIND ARTICLES
SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan