Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Synthesis, characterization and anti-tumor activity of Ti (IV) and Mn (II) complexes of N4[(E,2E)-3-Phenyl-2-propenylidene] isonicotinohydrazide

Author(s): Fahmideh Shabania, Shahriar Ghammamy

N4[(E,2E)-3-Phenyl-2-propenylidene] isonicotinohydrazide abbreviated as NPPI were synthesized and characterized. Ti (IV) and Mn(II) metal complexes of this ligand prepared by reaction of fluoride salt of Ti(IV) and chloride salt of Mn(II) with NPPI in dry acetonitrile. Characterization of the ligand and its complexes was made by microanalyses, FT-IR, 1H NMR, 13C NMR and UV–Visible spectroscopy. These new complexes showed excellent antitumor activity against two kind of cancer cells that are K562 (human chronic myeloid leukemia) cells and Jurkat (human T lymphocyte carcinoma) cells.


SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan