Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

Synthesis, characterization and biological evaluation of N-(5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl)-4-nitrobenzamide derivatives

Author(s): Kamaal Ahmeda, Chandrabose Karthikeyana, N.S.H.N Moorthy, Piyush Trivedi, Vikrant Vyas

A series of N-(5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl)benzamide derivatives 8 (a-g) have been synthesized. Structures of all the targeted synthesized compounds were evaluated by spectral analysis. All the synthesized compounds were evaluated for antifungal activities. Some of the synthesized compounds showed good antifungal activities at the concentration 100 μg/ml.