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Synthesis, characterization and biological evaluation of some pyrazoles derived from ?±,?²-dibromo 4,4'-difluoro chalcone | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Synthesis, characterization and biological evaluation of some pyrazoles derived from ?±,?²-dibromo 4,4'-difluoro chalcone

Author(s): Seranthimata Samshuddin, Badiadka Narayana, Balladka Kunhanna Sarojini, Rajagopalan Srinivasan, Vinayachandra, K. R. Chandrashekar

Pyrazole derivatives are prepared by condensing α,β- dibromo 4,4'-difluoro chalcone with various hydrazine derivatives. All these derivatives are characterized by NMR, IR and mass spectral data. All the synthesized products are screened for their in vitro antimicrobial and antioxidant properties. Some of the tested compounds exhibited significant DPPH scavenging activity.


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