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Synthesis, characterization and microbicidal activity of novel heterocyclic compounds having 2-Azetidinone | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Synthesis, characterization and microbicidal activity of novel heterocyclic compounds having 2-Azetidinone

Author(s): Viralkumar Modi, and Kirtikumar Goswami

reaction of Amino-aryl 1,3,4-oxadiazole derivatives into heterocyclic ring like, 2-Azetidinone. A series of 5-aryl-2- [(N,N-disubstitutedthiocarbamoylthio)-acylamino]-1,3,4-oxadiazoles were tested against various microorganisms. Five compounds were found to have higher inflammatory activity than ibuprofen and the highest activity was revealed by 2-(3-pyridyl)-5-ethylamino-1,3,4-oxadiazole.


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