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Synthesis, characterization and in-vitro biological evaluation of urea analogue of tetrazolo[1,5-a]pyrimidine | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Synthesis, characterization and in-vitro biological evaluation of urea analogue of tetrazolo[1,5-a]pyrimidine

Author(s): Dharmesh Pansuriya, Kalpesh Menpara, Naresh Kachhad iya, Jignesh Menpara and Kartik Ladva*

A series of N-(substituted aryl)-4-(4-(4-fluorobenz yl)-7-(4-methoxyphenyl)-5-methyl-4,7-dihydrotetrazo lo[1,5- a]pyrimidine-6-carbonyl)piperazine-1-carboxamidehav e been synthesized. The structures of all synthesiz ed compounds have been delineated by using 1 H NMR, Mass and IR. All the synthesized compounds w ere screened for their in-vitro antimicrobial activity.


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