GET THE APP

Synthesis, characterization, theoretical study and antibacterial studies of N(4- substitution phenylcarbamothioyl)biphenyl-4 carboxmide derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis, characterization, theoretical study and antibacterial studies of N(4- substitution phenylcarbamothioyl)biphenyl-4 carboxmide derivatives

Author(s): Hanan A. AL-hazam, Abas Fadhel and Hyder Abeduljaleel Rhadi

New compounds of N(4-substitution phenyl carbamothioyl) biphenyl-4-carboxamide derivatives have been prepared by first making biphenyl carbonyl isothiocyanate from ammonium thiocyanate and biphenyl carbonyl chloride, and then treating this products with primary amine to give products monothiourea, N- (phenylcarbanothioyl) biphenyl 4-carboxamide (1); N(p – tolylcarbmothoyl) biphelyl – 4 – carboxamide ( 2 ) and bisthiourea; N, ??(1,4- phenylenebis (azanediyl) bis (thioxo methylene) dibiphenyl-4-carboxamide(3)and N,??(1,2-phenylene bis (azanediyl) bis (thioxo methylene) dibiphenyl-4-carboxamide (4). The structures of these compounds was characterized spectroscopy, theoretically and biological activity; the anti-bacterial activity indicated that compounds possessed a broad spectrum of activity.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry