Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Synthesis of 2-substituted aryl-4-oxo-1,3-thiazolidine derivatives of indole : a new class of biological active compounds

Author(s): Adesh Dubey, S.K. Srivastava and S.D. Srivastava

A simple and efficient method has been developed for the synthesis of various 2-substituted aryl- 4-oxo-1,3-thiazolidine derivatives of indole using conventional and microwave irradiation techniques. The series of 2-substituted aryl-4-oxo-1,3-thiazolidine derivatives synthesized, were structurally confirmed by analytical and spectral data and evaluated for their antitubercular and antimicrobial activities. Some compounds showed that promising antitubercular and antimicrobial activities


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