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Synthesis of 3 (N(1,3dioxo 1H benzo[de]isoquinolin- 2(3H)-yl)alkyl)-2-(4- substituted) phenylthiazolidine-4-carboxylic acid. | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Synthesis of 3 (N(1,3dioxo 1H benzo[de]isoquinolin- 2(3H)-yl)alkyl)-2-(4- substituted) phenylthiazolidine-4-carboxylic acid.

Author(s): J. Ramchander

Regioselective synthesis of 3(n(1,3dioxo1Hbenzo[de] isoquinolin-2(3H)-yl)alkyl) -2-(4-substituted) phenylthiazolidine -4-carboxylic acid were performe d by coupling of 2-aryl-thiazolidin-4-caboxylic aci ds respectively with N-( ω -bromoalkyl)-1,8-naphthalimideusing K 2 CO 3 in DMF medium. The structure of all the new compoundswere characterized by IR, 1 H-NMR, 13 C-NMR, and Mass spectral data.


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