Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Synthesis of acrylic copolymers and their antimicrobial screening

Author(s): Rajesh J. Patel , Zarana H. Patel, Bindu C. Patel and Bhavesh P. Dave

Monomer vanillin methacrylate(VMA)was synthesized byreacting o-vanilline with methacryloylchloride. The monomercharacteristics was identified by Fourier transform infrared spectroscopy (FT-IR) and 1H-NMR spectroscopy. Homo-polymer and co-polymers of VMA with hydroxyl ethyl methacrylate(HEMA) at different feedcomposition was prepared by free radical solution polymerization at 70 ±2°C using 2,2’- azobisisobutyronitrile(AIBN) as an initiator and N,N-dimethylformamide (DMF). Antimicrobial activity of the polymers was also investigated against various bacteria, fungi and yeast.