Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Synthesis of �²-amino carbonyl derivatives of coumarin via Mannich-type reaction catalyzed by Zirconium oxychloride
Author(s): K. Logaiya, S. P. N. Sudhan, H. Ramadoss and S. Sheik MansoorA series of β-amino carbonyl compounds containing coumarin was synthesized by a three component Mannich reaction of 3-acetyl coumarin, aromatic aldehydes and aromatic amines in the presence of zirconium oxychloride ZrOCl2 .8H2Oas a catalyst. The present methodology offers several advantages such as high yields, simple procedure, low cost, short reaction times, mild reaction conditions and use of a reusable catalyst
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Citations : 25868
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