Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Synthesis of coumarins via Pechmann reaction using Cr(NO3)3. 9H2O as a Catalyst under microwave irradiation

Author(s): M Hari Krishna and P Thriveni

Cr(NO3)3. 9H2O is used as an efficient catalyst in the reaction of phenols with ethyl acetoacetate (via Pechmann reaction) in solvent-free media leads to the formation of coumarin derivatives using microwave irradiation in excellent yields with good purity.


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