Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Synthesis of New Bis-Schiff bases via environmentally benign grindstone technique

Author(s): S.B.Chavan, S.B.Zangade, S.S.Mokle and Y.B.Vibhute

Grindstone chemistry was used for the preparation of new bis-Schiff bases from 1,2-ethylene diamine and substituted benzaldehyde/acetophenones. Time required for formation of the bis- Schiff bases and yield of the products were compaired with conventional method. This method provides several advantages such as environmental friendliness, simple work-up procedure, and short reaction time with excellent yield.