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Synthesis of new series of 7-methyl-4-(5-aryl-[1,3,4] oxadiazol-2-yl methyl)-chromen-2-one and its derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Synthesis of new series of 7-methyl-4-(5-aryl-[1,3,4] oxadiazol-2-yl methyl)-chromen-2-one and its derivatives

Author(s): Sudugu Ramakrishna Reddy, Ch. Venkata Ramana Reddy and B. Satyanarayana

A new series of 7-methyl-4-(5-aryl-[1,3,4]oxadiazol-2-ylmethyl)-chromen-2-one and its derivatives have been synthesized in good yields from three intermediates, such as (7-methyl-2-oxo-2H-chromen-4-yl)-acetic acid ethyl ester, (7-methyl-2-oxo-2H-chromen-4-yl)-acetic acid hydrazide and (7-methyl-2-oxo-2H-chromen-4-yl)-acetic acid benzylidene-hydrazides by using commercially available (7-methyl-2-oxo-2H-chromen-4-yl)-acetic acid as raw material.


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