Synthesis of Novel Chromenes as Cytotoxic Agents | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Synthesis of Novel Chromenes as Cytotoxic Agents

Author(s): Manal M. Kandeel, Aliaa. M. Kamal, Eman K. A. Abdelall and Heba A. H. Elshemy

Novel substituted chromenes, chromenopyrimidine derivatives and chromenotriazolo-pyrimidines were synthesized. Several compounds were evaluated for their antitumor activity, most of them revealed promising cytotoxic activity against breast cancer cell line MCF-7 in comparison to colchicine as positive control.


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