Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Synthesis of novel pyrrolobenzodiazepine-quinoxaline hybrid molecule

Author(s): Tejeswararao Dharmana and Base S. D.

Synthesis of novel pyrrolobenzodiazepine-quinoxalin e hybrid molecule is described. This compound was p repared by linking C-9 of ( 9 ) with an 3-(quinoxalin-2-yl)aniline ( 5 ) through Buchwald–Hartwig reaction in good yields. Chemical structures were established by IR, 1 H NMR, 13 C NMR and mass spectral studies.


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