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Synthesis of phenyl pyrazolines and their derivative as antimicrobial and antifungal agents | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Synthesis of phenyl pyrazolines and their derivative as antimicrobial and antifungal agents

Author(s): Chandrakant Patel and C. P. Bhasin

A series of 2-Chloro-3-(1-phenyl-3-aryl-4,5-dihydro-1H-pyrazole-5-yl)-7-(trifluoromethyl) quinoline was synthesized by the action of -[2-Chloro-7-(trifluoromethyl) quinoline-3-yl]-1-phenylpre-2-en-1-one on phenyl hydrogen. The structures of the synthesized compounds have been established on the basis of their elemental analysis and spectral (IR, 1H NMR) studies. Further they have been screened for their antibacterial and antifungal activity.


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