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Synthesis Of Phenyl Tetrazolyl Hexa Hydropyranochromene Derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Synthesis Of Phenyl Tetrazolyl Hexa Hydropyranochromene Derivatives

Author(s): Rateesh Vanam, Prasanna Bethanamudi, M Ravinder and Amarnath Velidandi*

Novel series of bis-pyranotetrazole derivatives have been developed by using resorcinol as starting compound with involvement of substituted aromatic aldehydes (a-e), malononitrile in pot condensation. During the reaction 2,8-diamino-4,6-bis (substituted phenyl)-4,6-dihydropyrano[3,2-g] chromene-3,7-dicarbonitrile 1(a-e) and 2,8-dioxo-4,6-bis (substituted phenyl)-2,3,4,6,7,8-hexahydropyrano [3,2-g] chromene-3,7-dicarbonitrile 2(a-e) formed as intermediates. The synthesized compounds were confirmed by their IR, NMR and Mass spectral data.


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