GET THE APP

Synthesis of some new antimicrobial 5,6,7,8- tetrahydropyrimido[4,5-b]quinolone derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis of some new antimicrobial 5,6,7,8- tetrahydropyrimido[4,5-b]quinolone derivatives

Author(s): Maher A. El-Hashash, Sherif M. Sherif, Azza A. E. Badawy, Huda R. M. RashdanTetrahydroquinoline, Pyrimidoquinolines, Hydrazonoyl halides, Antimicrobial activity

2-Amino-1-aryl-1,4,5,6,7,8-hexahydro-4-phenylquinoline-3-carbonitrile derivatives were synthesized by the reaction of cyclohexanone (1) with 2-benzylidinemalononitrile (2) and the appropriate of aniline derivatives. The reactivity of some of these newly synthesized derivatives toward carbon disulfide and further toward hydrazonoyl halides were also studied. In addition, the antimicrobial activity of the newly synthesized derivatives was reported.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry