Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Synthesis of Some Novel Chalcone Containing Pyrazole Moiety

Author(s): Amol J Shirsat, Sunil S Bhagat, Ajit K Dhas, Gopal K Kakade

A green, efficient and rapid procedure for the synthesis of novel chalcone derivatives containing pyrazole moiety has been developed through the condensation of various pyrazole aldehyde and ketone, in the presence of Potassium Hydroxide (KOH) in Ethanol (EtOH). This method has the advantages of operational simplicity, and high yield of products via a simple experimental and work-up procedure.