Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Synthesis, spectroscopic and anti-cancer studies of fatty acid analogue of 2, 6-Diisopropylphenol

Author(s): Ali Mohammad, Fauzia Bano Faruqi and Jamal Mustafa

10-Undecenoic acid possessed anti-fungal, anti-bacterial, antiviral and anti-diabetic activities, but, there are a few reports indicating that the derivatives of this compound may also affect cellular processes related to cancer. Propofol (2, 6-diisopropylphenol) is a potent intravenous hypnotic agent which is widely used for the induction and maintenance of anesthesia and for sedation in the intensive care unit. Propofol also possess anti-cancer properties in addition to its sedative effects. The present study describes the synthesis, characterization and evaluation of a novel anticancer conjugate, 1-isopropyl phenol undece-10’-noate.


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