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Synthesis, structural elucidation and anti-microbia l screening of quinoline based s-triazinyl substituted aryl amine derivative s | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Synthesis, structural elucidation and anti-microbia l screening of quinoline based s-triazinyl substituted aryl amine derivative s

Author(s): Jyotindra B. Mahyavanshi *1 , Maharshi B. Shukla 2 , Kokila A. Parmar 2 and Jayesh P. Jadhav 2

A series of ten 2,4,6-trisubstituted s-triazines wa s synthesized with 4-Hydoxy benzonitrile, benzimida zole and different substituted arylamine derivatives and all the products were characterized by conventional and instrumental methods. The title compound was then e xamined for their in vitro microbial activity again st gram negative bacteria and gram positive bacteria and two fungal species. Structure of final compound was affirmed by IR, 1 H NMR, Mass Spectra and followed by elemental analy sis.


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