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The antibacterial activity of substituted 4-(hydroxymethyl)-5,5-dimethyl- 2,5-dihydro-2-oxofurans | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

The antibacterial activity of substituted 4-(hydroxymethyl)-5,5-dimethyl- 2,5-dihydro-2-oxofurans

Author(s): Gayane G. Tokmajyan, Lusine V. Karapetyan*, Rima V. Paronikyan and Hrachya M. Stepanyan

The antibacterial activities of 4-(hydroxymethyl)-5,5-dimethyl-2,5-dihydro-2-oxofuran derivatives have been evaluated. They exhibited high antibacterial activities in vitro and in vivo. These compounds, especially compound 1, definitely exceeded norsulfazole and furazolidone in case of study in vitro. They had analogous advantage in respect of norsulfazole during the study in vivo.


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