The determination of profenofos insecticide residue in cabbage (Brassica oleracea L.) by using gas chromatography-flame photometric detector (FPD) had been investigated. The cabbage was collected from Koto Baru area, Tanah Datar district, West Sumatra. The results showed that the cabbage was contain profenofos residue. The unwashed cabbage, washed with water, and washed with detergent has an average residue 0.220, 0.075, and 0.068 (ppm), respectively. The residue levels from these sample do not exceed the Maximum Residue Limit (MRL) that established by Indonesian National Standard (SNI) and the Regulation of the Ministry of Agriculture number 88 in 2011 that is 1 (ppm).